Received: 10.07.2023/ Accepted: 30.11.2023/ Published online: 29.12.2023
УДК 612.176.2 – 612.176.4
DOI 10.53511/PHARMKAZ.2024.56.52.002
M.B. BAURZHAN1, N.S. SAGANDYKOVA2, K.B. ABZALIEV3, K.S. AKHMETOVA3, M.K. MUSIMKHAN3, K.S. ABSATAROVA3
1Academy of Physical Culture and Mass Sports, Astana, Kazakhstan
2Nazarbayev University, Astana, Kazakhstan
3Al-Farabi Kazakh National University, Almaty, Kazakhstan
THE ROLE OF IL1RL1(SST2) IN MYOCARDIAL STRESS AND NON-ADAPTIVE
REMODELING DEVELOPMENT OF HIGH PHYSICAL ACTIVITY INDIVIDUALS
Resume: Sudden cardiac death (SCD) remains one of the most pressing global health problems. The United
States National Young Athlete WBC Registry data show a progressive increase of SCD over the past 2.5
decades, averaging 6% per year. Despite this, there are no SCD statistics in the Republic of Kazakhstan.
To study the early SCD predictors is one of the urgent tasks of modern healthcare. This review discusses
the modern biomarker IL1RL1(ST2) used to diagnose SCD, myocardial fibrosis, and heart failure.
Key words: myocardial fibrosis, sudden cardiac death, diagnostics, biomarker, IL1RL1(ST2).
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