Received: 20.11.2023 Accepted: 25.01.2024 Published online: 29.02.2024
UDC 616.314-089(045)
DOI 10.53511/PHARMKAZ.2024.43.99.047
M.А. Mugalbayeva1, U.R. Mirzakulova1, G.B. Zaitenova2, Z.S.Uglanov1
1 Asfendiyarov Kazakh National Medical University, Almaty, Republic of Kazakhstan
2 Kazakh-Russian Medical University, Almaty, Republic of Kazakhstan
ENHANCING OSTEOGENESIS: OSTEOPLASTIC MATERIAL WITH PLASMOGEL AND PLATELET-ENRICHED PLASMA
Resume. This article is a comprehensive exploration of the clinical and radiological findings derived from the
utilization of osteoplastic synthetic material, combined with plasma gel and platelet-rich plasma, to facilitate
and augment local osteogenesis subsequent to the atypical extraction of the lower third molar. The study,
comprising 80 patients, was meticulously divided into two distinct groups: the experimental group and the
control group. The strategic utilization of osteoplastic synthetic material in conjunction with plasmogel for
bone wound filling, along with the introduction of plasma enriched with platelet factors into the transitional
fold of the surgical site, emerged as a pivotal approach. This multifaceted technique not only acted as a
robust defense against wound infections but also exhibited a remarkable reduction in the frequency of
postoperative inflammatory complications, impressively plummeting from 10% to a mere 2.5%. Radiological
assessments, notably through X-ray examinations, provided compelling evidence of an accelerated and
substantially reinforced reparative regeneration of bone tissue within the void left by the extracted lower
third molar.
The primary and overarching objective of this comprehensive study was to meticulously scrutinize and
document the outcomes arising from the meticulous implementation of osteoplastic synthetic material in
conjunction with plasmogel and platelet-rich plasma. This innovative approach was systematically applied to
catalyze and amplify local osteogenesis, predominantly in the aftermath of the intricate and atypical extraction
of the lower third molar, shedding light on the transformative potential of this multifaceted intervention in
clinical practice.
Key words: Difficult Eruption, Lower Third Molar, Atypical Tooth Extraction, Osteoplastic Synthetic Material,
Plasma Gel, Plasma Enriched with Platelet Factors.
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