Received: 20.11.2023 Accepted: 31.01.2024 Published online: 29.02.2024
УДК 616.993(574)
DOI 10.53511/PHARMKAZ.2024.24.30.013

Saule Maukayeva1, Nazym Kudaibergenova1, Saya Karimova1, Yerbol Smail1, Madi Toleukhanov1
1Semey Medical University, NCJSC, Semey, Kazakhstan.

Resume: Brucellosis is a zoonotic infection and therefore an important public health problem in the world.
More than 0.5 million cases of brucellosis in humans are registered annually. Endemic areas for brucellosis
include countries with developed animal husbandry. Kazakhstan is among the twenty-five countries with the
highest incidence of brucellosis. Among the post-Soviet countries, Kazakhstan ranks second after Kyrgyzstan
in the incidence of brucellosis. In recent years, 2500-3500 cases of human disease have been registered
annually in the country, of which about 600 are children under the age of 14. The problem of brucellosis in
Kazakhstan is caused by the agricultural orientation and prevalence of small cattle, which is the carrier of
the most pathogenic Brucella melitensis. 42.2% of Kazakhstanis live in rural areas, and their main income
is animal care. More than 85% of human brucellosis cases have been registered in 4 southern regions
where animal husbandry (sheep breeding) is developed. Despite the long history of campaigns to combat
brucellosis, Kazakhstan has not overcome this threat to public health. Brucellosis can affect many organs
and systems. Complications of brucellosis are usually about 30 percent. Neurological damage occurs in up
to 10% of cases. Manifestations include meningitis (acute or chronic), encephalitis, brain abscess, myelitis,
sciatica and/or neuritis (with damage to cranial or peripheral nerves). The article presents rare clinical cases
of neurobrucellosis on the background of concomitant diseases.
Keywords: brucellosis, Kazakhstan, epidemiology, nervous system, treatment, clinical case.

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