Received: 19 August 2026
Accepted: 05 October 2026
Published online: 30 October 2026
UDC: 615.322
SRSTI: 31.23.39
DOI: 10.53511/pharmkaz.2026.5.16
Article type: Scientific Review Article
OBTAINING PEPTIDES FROM MEDICINAL PLANTS AND PROSPECTS FOR THEIR USE IN PHARMACEUTICAL COSMETOLOGY (NARRATIVE REVIEW)
Talasbay K.S. ¹, Ustenova G.O. ¹, Satmbekova D.K. ², Sarsenova L.K. 2
¹Asfendiyarov Kazakh National Medical University, Almaty, Kazakhstan
²Al-Farabi Kazakh National University, Almaty, Kazakhstan
Introduction. The cosmetic market in Kazakhstan is highly dependent on imported products, which account for more than 98% of the market. Under these circumstances, the search for accessible and promising locally sourced materials for the development of cosmetic products is of particular importance. Medicinal plants have attracted considerable interest due to their rich composition of biologically active compounds, which may provide a wide range of beneficial effects on the skin. Among plant-derived compounds, bioactive peptides represent a promising yet insufficiently studied group of natural ingredients with potential applications in cosmetology.
This review aims to analyze plant sources of peptides, their biological properties and mechanisms of action, as well as their potential applications in cosmetology.
Methods. A narrative review of publications available through PubMed, Scopus, Google Scholar, and CyberLeninka was conducted, focusing on plant-derived peptides, their production methods, biological activity, and potential applications in cosmetology. Findings were qualitatively compared with attention to the nature of the experimental evidence.
Results and Discussion. The literature analysis indicates that plant-derived peptides have considerable potential as functional ingredients in cosmetic products. However, the available evidence regarding their composition, properties, mechanisms of action, and practical applications in cosmetology remains limited and fragmented. One of the major challenges is the insufficient understanding of the relationship between peptide structure and biological activity, as well as the difficulties associated with obtaining stable and standardized peptide fractions from plant materials.
Conclusions. Further development of this field requires improvements in peptide isolation and purification methods, comprehensive evaluation of their stability and biological activity, and the development of approaches for standardizing plant-derived peptide ingredients in cosmetic formulations. Advancing research in these areas may contribute to the more effective utilization of plant-derived peptides and support their broader application in the cosmetic industry.
Keywords: plant peptides, cosmetology, medicinal plants, bioactive compounds, antioxidant activity.
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