Received: 04.05.2026
Accepted: 29.05.2026
Published online: 17.06.2026
UDC: 615.322 : 581.19 : 504.06
DOI: 10.53511/pharmkaz.2026.3.11
PROSPECTS FOR PHYTOCHEMICAL USE OF PLANTS OF THE GENUS
MACROTOMIA (ARNEBIA) AND THEIR ROLE IN RATIONAL NATURE
MANAGEMENT (REVIEW)
Abilova A.A. ¹*, Orynbassarova K.K. ¹, Karzhaubayeva A.D. ¹, Pernebekova R.K.¹,², Tursubekova B.I. ³
¹ Joint-Stock Company “South Kazakhstan Medical Academy”, Shymkent, Kazakhstan
² Khoja Akhmet Yassawi International Kazakh-Turkish University, Turkestan, Kazakhstan
³ 3 M. Auezov South Kazakhstan University, Shymkent, Kazakhstan
Introduction: Plants of the genus Macrotomia (Arnebia) are notable sources of bioactive compounds, distinguished by their diverse phytochemical content and extensive biological activities. The aim of the research work. To summarize and analyze data on the composition and distribution of biologically active compounds in plants of the genus Macrotomia (Arnebia), as well as to assess their role in ensuring the sustainable use of natural resources.
Materials and methods. The article is written as a review in accordance with the PRISMA 2020 guidelines.
Results and discussion. The analysis of the literature revealed anti-inflammatory, antimicrobial, antioxidant, and wound-healing properties of plants of the genus Macrotomia (Arnebia). These properties are associated with the presence of biologically active substances in the plant material, such as shikonin and its derivatives, naphthoquinones, and phenolic compounds. The scientific novelty of this work lies in the comprehensive systematization of data on the pharmacological activity of the genus Macrotomia (Arnebia) and the identification of common mechanisms of action.
Conclusion. Species of the genus Macrotomia (Arnebia) are among the plants with high resource potential for the development of new herbal remedies, as confirmed by scientific research devoted to the morphological, phytochemical, and ecological properties of these raw materials. Despite numerous studies on individual species, issues related to raw material standardization for practical use, safety assessment, and the development of sustainable approaches for the
conservation of natural populations remain insufficiently investigated. Thus, an integrated approach combining chemical, pharmacological, and ecological aspects highlights the scientific and practical significance of this study.
Keywords: genus Arnebia, genus Macrotomia, biologically active substances, medicinal plants, biodiversity
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