Received: 15.02.2023 / Accepted: 24.05.2023 / Published online: 30.06.2023
UDC 615.32:582.736(574)
DOI 10.53511/PHARMKAZ.2023.74.33.045
A.S. Keleke1, L.N. Ibragimova 1, G.T. Zhumashova1, A.G. Sabitova1, E.Sh. Sultanov1, Z.B. Sakipova1
1 Asfendiyarov Kazakh National Medical University, Almaty, Kazakhstan
KAZAKH PLANT SPECIES OF THE GENUS HEDYSARUM L.: DISTRIBUTION,
BOTANICAL DESCRIPTION AND PROFILE OF PHARMACOLOGICAL ACTIVITY
Resume: A review of Kazakhstani species of the genus Hedysarum L. (sweetvetch) has been conducted,
that includes 28 plant species with scientific names recognized by international floristic bases, 10 of which
are endemics. The ranges of distribution, botanical characteristics, phytochemical composition and profile
of pharmacological activity of some represented species were studied. The life form of all the studied
sweetvetches is represented by perennial herbs, the chemical composition of which is characterized by such
phenolic compounds as three isoflavonoids – ononin, formonononetin, formonononetin-7-O-β-D-glucoside-6′-
O-malonate and pterocarpan – medicarpin. It is established that the pharmacopoeial species of the genus
is Hedysarum polybotrys Hand.-Mazz, the most phylogenetically close to it is Hedysarum semenowii Regel
& Herder species, which commonly grows on the territory of the Central Tien Shan. This species is used
in folk medicine and is not inferior in its valuable properties to pharmacopoeial species, but it has not been
widely studied, which was the reason for its selection as an object for further research.
Keywords: medicinal plants, Hedysarum (sweetvetch), Hedysarum semenowii, flora of Kazakhstan, distribution,
botanical description, pharmacological activity.
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